Endocrine Abstracts

Background: Individuals with gender incongruence receive gender affirming therapy which is fundamental to sex reassignment. Cross sex hormone treatment both improves and impairs several surrogate markers of cardiovascular risk. In the aging population of transsexual persons, we are called to address clinical endpoints of the long-term gender affirming hormone therapy.Aim: Aim was to assess changes in the fasting serum lipid profile during gender affirmin...

Introduction: Secretory adrenal tumors sensitive to luteinizing hormone (LH) and/or human chorionic gonadotropin (hCG) are well documented in the literature. LH and hCG share a mutual LH/hCG receptor and a comparable physiological role.Objective: The aim of our study was to evaluate the response of adrenal steroids (cortisol, aldosterone and dehydroepiandrosterone sulphate (DHEAS)) to exogenous hCG stimulation in menopausal patients with adrenal incident...

Involutive hypoandria (late onset hypogonadism) is characterized by decline in serum testosterone and increase of gonadotropins. Changes of hypothalamo-pituitary-testicular axis sensitivity are influenced by primary testicular changes and altered neuroendocrine regulation during aging. To evaluate age-related changes in gonadotroph and Leydig cell sensitivity two groups were formed: 1) 35 men, 51.8±3.2 years old, BMI=28.2±3.1 kg/m2; 2) 32 men, 63.2±6....

One-hour (1 h) glucose level of the oral glucose tolerance test (OGTT) was proven to be a better predictor of insulin resistance (IR) in nondiabetic population than the two-hour (2 h) postload glucose level. Specifically, the 8.6 mmol/l cut-off was shown to be an early marker of impaired glucose tolerance (IGT). Previous studies have shown that nondiabetic patients with adrenal incidentalomas (AI) have higher IR than healthy control (HC). However, despite the subtle cortisol s...